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> Much more importantly, our use of medicines (antibiotics, antivirals, antifungals, etc.) have put extreme selective pressure on pathogens to evolve to become resistant to them.

I don't think that makes sense when comparing against the threat level of pre-antimicrobial times. It didn't matter that they weren't resistant before we had antimicrobial drugs. Lack of resistence was useless in cave man times.



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