A full mastectomy performed without anesthetic at the beginning of the XIX century, and the patient made a full recovery, surviving both the operation and the cancer into old age. This is nothing short of a miracle.
To put it in perspective, the germ theory of disease was virtually unknown and the medical professionals operated with the notion of "miasmas", foul odors and mists that carried diseases though the air.
Since it isn't in the main text, I will post it here copied from the transcript:
My dearest Esther, – & all my dears to whom she communicates this doleful
ditty, will rejoice to hear that this resolution once taken, was firmly adhered to, in
defiance of a terror that surpasses all description, & the most torturing pain.
Yet – when the dreadful steel was plunged into the breast – cutting through veins –
arteries – flesh – nerves – I needed no injunctions not to restrain my cries.
I began a scream that lasted unintermittingly during the whole time of
the incision – & I almost marvel that it rings not in my Ears still! so
excruciating was the agony. When the wound was made, & the instrument
was withdrawn, the pain seemed undiminished, for the air that suddenly
rushed into those delicate parts felt like a mass of minute but sharp
& forked poniards, that were tearing the edges of the wound – but when
again I felt the instrument – describing a curve – cutting against the grain,
if I may so say, while the flesh resisted in a manner so forcible s to oppose & tire the hand of the operator, who was forced to change
from the right to the left – then, indeed, I thought I must have ex-
-pired. I attempted no more to open my Eyes, – they felt as if hermeti
-cally shut, & so firmly closed, that the Eyelids seemed indented into
the Cheeks. The instrument this second time withdrawn, I concluded the
operation over – Oh no! presently the terrible cutting was renewed –
& worse than ever, to separate the bottom, the foundation of this dread-
ful gland from the parts to which it adhered – Again all description would
be baffled – yet again all was not over, – Dr Larry rested but his own
hand, & – Oh Heaven! – I then felt the Knife rackling against the breast
bone – scraping it! – This performed, while I yet remained in utterly
speechless torture, I heard the Voice of Mr Larry, – (all others guarded a
dead silence) in a tone nearly tragic, desire everyone present to
pronounce if he thought the operation complete, or if any thing more
remained to be done; ˄ or if they he thought the operation complete. The general voice was Yes, – but the finger of
Mr Dubois – which I literally felt elevated over the wound, though
I saw nothing, & though he touched nothing, so indescribably sensitive
was the spot – pointed to some further requisition – & again began
the scraping! – and, after this, Dr Moreau thought he discerned a
peccant attom – and still, & still, M. Dubois demanded attom after
attom. – My dearest Esther, not for days, not for Weeks, but for
Months I could not speak of this terrible business without nearly
again going through it! I could not think of it with impu-
-nity! I was sick, I was disordered by a single question – even
now, 9 months after it is over, I have a head ache from going on
with the account! & this miserable account, which I began
3 Months ago, at least, I dare not read, nor revise, nor read,
the recollection is still so painful.
To conclude, the evil was so profound, the case so delicate, & the
precautions necessary for preventing a return so numerous, that the
operation, including the treatment and the dressing, lasted 20 minutes! a
time, for sufferings so acute, that was hardly supportable – However, I
bore it with all the courage I could exert, & never moved, nor stopt them,
nor resisted, nor remonstrated, nor spoke – except once or twice, during
the dressings, to say “Ah Messieurs! que je vous plains! –” for indeed I
was sensible to the feeling concern with which they all saw what I en-
-dured, though my speech was principally – very principally meant
for Dr Larry. Except this, I uttered not a syllable, save, when so often
they re-commenced, calling out “Avertissez moi, Messieurs! Avertissez
moi! –” Twice, I believe, I fainted; at least, I have two total
chasms in my memory of this transaction, that impede my tying
together what passed. When all was done, & they lifted me up
that I might be put to bed, my strength was so totally annihi-
-lated, that I was obliged to be carried, & could not even sustain
my hands & arms, which hung as if I had been lifeless; while
my face, as the Nurse has told me, was utterly colourless. This
removal made me open my Eyes – & I then saw my good Dr Larry,
pale nearly as myself, his face streaked with blood, & its expression
depicting grief, apprehension, & almost horrour.
When I was in bed, – my poor M. d’Arblay – who ought to write
you himself his own history of this Morning – was called to me – &
afterwards our Alex.
To put it in perspective, the germ theory of disease was virtually unknown and the medical professionals operated with the notion of "miasmas", foul odors and mists that carried diseases though the air.