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Sex, food or water? How mice decide (nature.com)
81 points by rntn on Feb 23, 2023 | hide | past | favorite | 25 comments



  scientists treated male mice with a technique that mimics the effects of leptin, a hormone that acts
  on the brain to suppress appetite. Treated mice were more likely to approach female mice than their
  food bowls — even if the test rodents had been deprived of food for almost an entire day.

  The paper “addresses a huge gap in the field”, she says. “When you no longer need to eat urgently, it
  should free you up to do other things.”
That's.... the most obvious thing in the entire world. If you're hungry, you can't think about anything but food. If you're not hungry, you can think about things other than food.

We're looking at the next Ig Nobel prize winner, aren't we?


It seems obvious, but I think an important part of science is to remain skeptical and not accept things as fact because they’re “obvious.”

It very well could have turned out that the mice still chose to eat despite having no hunger. I for one am definitely prone to overeating past the point of satiating hunger, or eating even if I’m not hungry. I find it satisfying and a way to overcome boredom; or maybe a better example is my dog, who I’m pretty certain would eat himself to death if I left his kibble box unlocked.

It seems obvious that the sun revolves around the Earth, but we now know that isn’t true. :-)


I recall reading a funny article, by some guys at cornell if my memory does not fail me, that concluded that obesity rates were lower in europe because europeans would stop eating when they weren't hungry anymore. Whereas americans would stop eating when turning off the TV (and therefore would continue eating after being full).


Many things that seems obvious are really really wrong, that's why we came up with the scientific method


Proving the obvious is useful just not newsworthy.


Think another example. The sun evolves around the horizon. So are the stars and the moon. The earth is obviously the centre of the universe. Is it not? Now or course we have all the facts and arguments to back up otherwise.

But how do we know what we believed is really what what it is?


they didn't know what the result of their experiment would be. If it had come out differently, it would have sent them back to the drawing board.

they hypothesized that this particular drug/hormone intervention would have a particular effect, and an experiment was needed to confirm the hypothesis. Further experiments might show that they were even wrong even about this one, and there is some other interaction going on to fully explain what's going on.


If you want a dose of odd - this talk at Odd Salon from a few years ago on the Mouse Utopia experiments is pretty entertaining: https://www.youtube.com/watch?v=CG2Xh2JCoMY


As a parent I find it interesting that they don't have sleep in the list of options. F sex, water, food ... I could go for a nice nap.


funny--there's just an article about quolls that said that they travel so far to get laid that they become sleep deprived and die soon after


This is the way.


I’d be curious if the inverse is also possible, social interactions triggering the release of leceptin. Perhaps social interaction could cause feelings of satiety too?


> social interaction could cause feelings of satiety too?

depends on the circumstances, but I can imagine social interactions where food is served still causing me to at least ask for a phone number, so it's clear I'm not entirely sated.


That depends if the food gave you garlic breath or not.


Experiments on mice show that the hormone leptin influences not only appetite but also pursuit of the opposite sex.

Wouldn't be the first creatures to have an appetite for sex.



Mice can decide? I CAN'T DECIDE!


This is great content, I enjoyed reading this comment, but HN has been such a wonderful place for such a wonderful time because we just don't do the reddit thing around here :)

Let reddit be reddit and HN be HN please.


Why single out this comment? None of the comments on this mouse-sex article have been particularly erudite


not any of the ops, but the alternative to singling out this comment would be replying to all of the others, or remain silent in face of the mob. I don't think his choice requires defense than that.


Paradoxically, replying with a general comment about the low state of the comment section would be pretty Redditesque.

"I know this will get downvoted but..."


I replied to this comment to explain why I downvoted it, because it feels bad to not understand why you're downvoted.


Don't they always pick sex (if available)?


Not according to the article


Oh?

> even moderately hungry mice prefer to socialize with the opposite sex than to eat, researchers have found.

.. but I understand what you're referring to much further down. Starvation wins.




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