> Women's mortality starts to match men's as they progress on menopause.
Doctors used to prescribe women horse-derived estrogen (PREMARIN - made from PREgnant MARes' urIN) on the mistaken belief that women were deficient in estrogen after their cycles stopped. "Prescription horse piss" doesn't sell very well to people who don't necessarily trust their doctors, so the medical industry mostly switched to selling a synthetic bio-identical estrogen to treat women's supposed "estrogen deficiency".
But really it's the loss of a monthly Progesterone surge, from the post-ovulation luteal phase of the cycle, that's behind women's health advantages over men. When ovulation stops, women's death rates rapidly increases to match men's rates.
Supplemental progesterone can be taken transdermally or via injections. Most of the progesterone in a pill is lost to the first-pass metabolism: https://en.wikipedia.org/wiki/First_pass_effect
Doctors used to prescribe women horse-derived estrogen (PREMARIN - made from PREgnant MARes' urIN) on the mistaken belief that women were deficient in estrogen after their cycles stopped. "Prescription horse piss" doesn't sell very well to people who don't necessarily trust their doctors, so the medical industry mostly switched to selling a synthetic bio-identical estrogen to treat women's supposed "estrogen deficiency".
But really it's the loss of a monthly Progesterone surge, from the post-ovulation luteal phase of the cycle, that's behind women's health advantages over men. When ovulation stops, women's death rates rapidly increases to match men's rates.
Supplemental progesterone can be taken transdermally or via injections. Most of the progesterone in a pill is lost to the first-pass metabolism: https://en.wikipedia.org/wiki/First_pass_effect