That gave me the biggest thing to think about. I had the most web experience with Django but it's been years since I used it in anger. In the meantime I'd been using FastAPI and knew enough of its warts, so I went with FastAPI + Postgres.
But if I was just starting out trying to learn a web stack like GP, I'd say absolutely don't pick FastAPI, use Django + Postgres + Bootstrap + htmx and you'll be happy.
