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Old mice grow young again in study. Can people do the same? (cnn.com)
7 points by harambae on Jan 13, 2023 | hide | past | favorite | 2 comments



> The experiments show aging is a reversible process, capable of being driven “forwards and backwards at will,” said anti-aging expert David Sinclair, a professor of genetics in the Blavatnik Institute at Harvard Medical School and codirector of the Paul F. Glenn Center for Biology of Aging Research.

I may not be a scientist, and I am usually one to defer to authority, but I do not agree with this verdict. I am of the belief that aging cannot be stopped or reversed. And I don't indulge in the childish fantasy that it will be one day possible for a human to live 200 years.

Show me you can keep 100 mice alive for 40 years and I may change my mind.


Belief does not count as scientific process...Maybe start at the study findings

"...Using a system called “ICE” (inducible changes to the epigenome), we find that the act of faithful DNA repair advances aging at physiological, cognitive, and molecular levels, including erosion of the epigenetic landscape, cellular exdifferentiation, senescence, and advancement of the DNA methylation clock, which can be reversed by OSK-mediated rejuvenation. These data are consistent with the information theory of aging, which states that a loss of epigenetic information is a reversible cause of aging..."

"Loss of epigenetic information as a cause of mammalian aging" - https://www.cell.com/cell/fulltext/S0092-8674(22)01570-7




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