Which one, the part that set and setting matter? Read basically any paper on psychedelic therapy.
That psychedelics can worsen mental disorder?
Psychedelics can help you process bad experiences, and it can generate new ones. You can unlearn unhealthy biases or gain new ones. The papers tend to discuss this.
That all derives from the fact that set and setting are crucial.
And I didn't suggest worsening was likely, but I think it's about just as likely as stumbling into a real treatment effect by accident, which is what I said. I'm not sure what data exists on the relative probabilities here, probably fairly little.
Most of the time, you'll just achieve nothing at all other than maybe an afterglow that makes you think you're better for a couple of weeks.
I've used a lot of different psychedelics in different settings over the years(pribably somewhere around 100 experiences with something like 10 different psychedelic drugs), Exactly once I've had a concrete, non-temporary improvement in mental health. Another time I had such a bad experience I took me months to properly recover.
Most of the times I felt like progress was being made, but it turned out just to be an afterglow effect that quickly went away.
If your symptoms subside for a couple of weeks, and you repeat the experience every couple of weeks, it’s hard to see how this is much different from taking SSRIs. They certainly don’t claim to cure anything either.
What would be good data which is actually practical and ethical to get? I hope no review board would approve a plan of "group A will have a professional therapist following protocol XYZ, and group B will be handed a dose and a printout of a reddit thread and told to have fun"
Sometimes we don't have good data for good reasons.
