This was the first google result for NextDNS CLI - https://github.com/nextdns/ne...

This was the first google result for NextDNS CLI -

looks like it proxies standard DNS traffic to NextDNS via DOH, and does some other fancy stuff including caching, zeroconf discovery, and conditional forwarding.

Dang, this looks like a nice option for my home setup - I may give it a try!!