I think it's fair to say though it was intended to be a move away from the main PC microprocessor line (which you can argue traced a path through 8080 to 8086 and beyond ) and ultimately replace it at the high end - so in spirit similar to Itanium even if not an 'x86 replacement'.
x86 traces it's DNA all the way back to the 8008 which led to the extended 8080 which led to the backward compatible 8085 then 8086 and the x86 architecture.
8008 was almost a full decade before the launch of the iAPX 432.
The roots of x86 were in one of the first major ISAs ever created (and something like the 2nd or 3rd microprocessor architecture) which is pretty remarkable when you think about it.