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Those are interesting analogies, particularly for the RNA. Thanks for sharing them.


Thanks. I agree that they are interesting. (I wrote them :) .) But I can think a few reasons why they are wrong. Anyway, I think they are useful to understand the difference between prions and rna, and why prions are not a good proposal for the origin of life.


Good points, I like the analogies. I would also not classify prions as life originators, but rather thinking if a similar model would have been employed by an intermmediate non-nucleotide based replicator. So basically chemical folders that would gradually evolve the replicator molecular complexity.


Nobody is sure, and I'm not an expert in this field, but looking at https://en.wikipedia.org/wiki/RNA_world#Alternative_hypothes... there are a few ideas.

I think the https://en.wikipedia.org/wiki/PAH_world_hypothesis is somewhat similar to your idea. IIUC they don't self reproduce, they just grow in a random order in a pattern. And the proposal is that it 's good to support the RNA bases for a small time to make it easy to build small chains.

[I remember to have read something like that about clay or crystals, but I can't find it now in the article in Wikipedia. Perhaps the idea was abandoned a long time ago.]




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