Isn’t jQuery mostly dominant in stats because it’s included in WordPress by default (definitely in 90% of Wordpress themes). It’s been a while since I checked so this could be out of date.
When using classic Angular (some time ago) with Bootstrap I ended up rewriting the JS parts of any bit of Bootstrap we used as Angular components for ease of debugging (I know lots of people hated Angular but it was still easier to only debug one framework-ish thing at once).
The existence today of e.g. react-bootstrap suggests that I'm not the only one to have had this idea.