One approach is to eliminate congeners, the stuff that adds the flavor to alcohol but is also strongly related to kerosene. There have been hangover pills that actually do seem to work to some extent, RU-21 and Chaser, both no longer sold I think. I've tried both. RU-21 is weird, I can't describe it, I didn't like it, it made everything taste sweet. Chaser did seem to reduce hangovers but also made the mind clearer while drinking, which reduced the fun somewhat, which tended to make people drink more. Not sure why they were taken off the market, I've never been able to find an explanation. Activated carbon pills are also used by some people to reduce hangovers, which I think absorbs some of the congeners.
I think the main problem is the breakdown of alcohol into acetaldehyde, it's the acetaldehyde that is poisonous. We've found methods for dealing with other poisons after ingestion, maybe some of the same methods would work for acetaldehyde.
Drinking alcohol also depletes the body of water and B vitamins.
I think the main problem is the breakdown of alcohol into acetaldehyde, it's the acetaldehyde that is poisonous. We've found methods for dealing with other poisons after ingestion, maybe some of the same methods would work for acetaldehyde.
Drinking alcohol also depletes the body of water and B vitamins.
So those areas seem like the place to start.