You can host Seafile yourself, which has end-to-end encrypted libraries[1] and version control. There are also hosted versions listed in their partners page [2] if you'd rather not manage that yourself. Apps are available for most platforms, I believe.
I don't know how good macOS support for FUSE style filesystems is these days, but you could work around the encryption problem by mounting something like an EncFS file system over your cloud drive (Homebrew seems to have it?). It'll make the files virtually inaccessible to other tools (like the GDrive web UI) but it'll protect your files and should keep away most unnecessary sync operations. I don't know if and if or how it conflicts with the GDrive application, though.
I don't know how good macOS support for FUSE style filesystems is these days, but you could work around the encryption problem by mounting something like an EncFS file system over your cloud drive (Homebrew seems to have it?). It'll make the files virtually inaccessible to other tools (like the GDrive web UI) but it'll protect your files and should keep away most unnecessary sync operations. I don't know if and if or how it conflicts with the GDrive application, though.
[1]: https://help.seafile.com/security_and_encryption/use_encrypt...
[2]: https://www.seafile.com/en/partner/