Not quite 'unknown' e-mails as I would think of them - these were e-mails that appeared to be from co-workers and addressed specifically to another individual, hence spear-phishing, rather than just phishing. For all intents and purposes, it probably had all the appearances of a legit e-mail.
If I understand it, then, someone opens the initial payload which allows malware to be downloaded- and this downloaded malware orchestrates the "spear phishing?"
I haven't seen this as I've been out of an organization for quite a while. Thanks for clarifying.