It's more important to think about FLOW and also the quality of air exiting an air-handling system. BTW, how often are those ducts cleaned, if ever?
I would personally love a well designed slightly positive pressure dwelling with particle scrubbed inflow and egress (some kind of circulated water system like industrial sites have). Get rid of that pollen and everything else please.
There's an interesting system called "Phenomenal Aire" that I recently installed. It sort of achieves what you're talking about, but uses a very different mechanism called "Cold Plasma Generation" (caused by dielectric barrier discharge). The air smells noticeably "fresher" though that might just be due to the ozone. It does seem to have a dramatic neutralizing effect on VOCs [0].
Interesting article re: use in meat packing plants [1].
It is. It's a strong oxidizer and damages your lungs. It makes the house smell better because it oxidizes volatile organic compounds in the air, but it's horrible for you.
I would personally love a well designed slightly positive pressure dwelling with particle scrubbed inflow and egress (some kind of circulated water system like industrial sites have). Get rid of that pollen and everything else please.