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I'm not so confident RCTs of nutrition are unethical. The data are too damn valuable for society to ignore. Perhaps participants could be informed and willing to partake in the challenge trials, which although these participants might not be reflective of the overall population, we can get a better sense than correlational studies.

Humans are incredible explorers, self-sacrificing for the greater (perceived) good. We should consider continuing our legacy by understanding ourselves better through rigorous science. (And hopefully end the historical legacy of making thousands of other species extinct via our exploration.)

I believe the Journal of Controversial Idea (https://journalofcontroversialideas.org/) will explore some of these topics, shortly.




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