I was going to reply saying I don’t want tiny pieces of radioactive material all over my house/globe, but then realized I have a tiny explosive (battery) in my hand and littered all of my house.
People freak out when they hear "nuclear" and "radiactive", but there are 3 types of radioactivity.
Alpha and low energy beta emitters such as those used in nuclear batteries are not dangerous at all if shielded properly. In fact they are MUCH easier to shield than shielding a Lithium battery from the possibility of fire.
It's gamma emitters that are much harder to shield properly.
> Alpha and low energy beta emitters such as those used in nuclear batteries are not dangerous at all if shielded properly.
Read: if there is no feasible route for them to be aspirated, ingested, or get into your eyes.
Making a new device that has this property seems to be a pretty straightforward problem that we know how to do. The problem comes when an old device has been damaged or destroyed kinetically or via pyrotechnics.
It's more complex than that in case of a failure, because ingesting an alpha or beta emitter - directly, or through the food chain - is going to be dangerous to health. Can't exactly line your intestines with lead.
And while giving RTGs to general population isn't the brightest idea, it's stupid to consider these issues as a wholesale dealbreaker for nuclear technologies.