Of course you don't spend it all yourself, but if your parents put $1B in your non-profit you can pretty easily get a 5% ROI and safely spend 45 mil / year on actual donations and 5 mil / year on your 'business trips'.
You could do that, but it doesn't achieve the goal that was being discussed.
Spending money on trips is not a "ROI" (return on investment).
Plus, if you spend $5M personally on trips, that will most likely be caught as fraudulent. Because it clearly is. The IRS looks at what charities spend their money on.
Meta: I will try not to engage in these kinds of discussions on HN in the future since people have made it clear they don't want this information.