I'm interviewing 33 startups and they talk about how they got interested in entrepreneurship, ways they dealt with challenges such as finding cofounders, hiring, raising money, staying motivated, getting users, etc. It's the same Q&A approach as Founders at Work, but all of these guys are still in their early stages (although there are a few like Foursquare and GitHub that aren't as early stage).
The book title is mostly referring to the idea of making the process of doing a startup as open as possible--you're getting a pretty good view into how these founders think and deal with a lot of different problems. I'm not sure why, maybe it's because I know some of the founders personally, but these interviews are definitely more honest and cadid than most interviews I've read. I have probably only seen more swearing in a book while reading Catcher in the Rye.