Stop me if this is just too weird, but I believe if you rely on proprietary software then you should choose the platform where you get the best performance of that software.
There are a very finite number of HPC clusters available to any given researcher with a given grant. Each european country might have 1-10 available and you have to apply for compute time.
If you’re in a commercial setting, your company might have 1 cluster and N simulation programs.
