That's true, but if now there is central space freeing up in major cultural hubs like NYC and SF, maybe it could be cool. These places might, although to a lesser extent, have the customer base of affluent people to support new cultural spaces.
IMO that's a big open question. Anecdotally, I've heard of a lot of people moving away from these cities, but most of them say they intend to move back. Since the appeal of both cities is largely in activities that are unavailable now, this is plausible to me. But it's also plausible people will find they miss the city less than they expected.