It doesn't work that way. New drugs are assumed ineffective until proven otherwise. A government official with no medical training recommending an unproven drug based on a few anecdotes is the height of irresponsibility.
Currently the studies can't tell if HCQ is effective or not because all of them have been wasted opportunities for many different reasons, from too few patients, to absence of controls, to too late administration (the NEJM paper and the Lancet paper on lopinavir/ritonavir tell important lessons on this topic). We're in the "absence of evidence is not evidence of absence" territory.
I would say HCQ is a "lead" in the pharmacological sense (after all there's an effect in vitro), but of course there's no guarantee it will work properly (work as in "higher efficacy than placebo or other treatments") in vivo.
The reason for my comment is that the announcement by the "government official" (who was not the first, the first being the eccentric Dr.Raoult) turned what should have been scientific debate into a political flamefest (at least in the media). And science (aka, proper, randomized clinical trials) got lost in the way (at some point the U of Minnesota trial struggled to get new people).
I personally don't have any particular love for HCQ: chances are, like remedisivir, that if there is an effect, it is small. But I want to point out that so far science is still out on this one.
> I would say HCQ is a "lead" in the pharmacological sense
Agreed. I hope it gets proven effective too. This is a hot button issue for me because a family member needs HCQ for lupus and now cannot obtain it because of the statements of said government official. His words have caused actual harm, and this isn't the first time.
It doesn't work that way. New drugs are assumed ineffective until proven otherwise. A government official with no medical training recommending an unproven drug based on a few anecdotes is the height of irresponsibility.