This seems implausible for many reasons, it seems more likely that if we're living in a simulation, we'll have trouble figuring out how to proloxify the feeblegarps.
Yes. The idea is that if we "break out" of whatever simulation we purportedly exist within, none of the concepts in the enclosing universe would make any sense to us.
(I happened to be watching How A Plumbus is Made when I wrote the comment, btw).