Another one: https://github.com/facebookincubator/xar "XAR lets you package many files into a single self-contained executable file. This makes it easy to distribute and install... A popular example is Python application archives that include all Python source code files, as well as native shared libraries, configuration files, other data."
Have a repo for your code, vendorize every thing, build a binary including Python interpreter using a build system that emphasize on reproducibility (e.g. Bazel).
Alternatively you can build a docker image using Bazel (for reproducibility) and use tools like Droot to chroot into the image then run.
Is it possible to build a wheel for a unix platform on a windows machine, when the package and some of its dependencies have compiled portions? I'm trying to build a wheel with deps for exchangelib and have been struggling.