I feel like PowerBI is a good solution to overcome Excel's deficiencies while working well with Excel. It forces you to structure your data and define measures while being dyanamic, efficient and friendly to less structured inputs.
I have to give PowerBI a serious shot. We have it at my current place but nibody is really using so I need some spare time to dive into it.
Now, the more I think about it, the combination of MS Office, Power BI and MS Dynamics with a shopfront from, say Shopify would make up a quite nice e-commerce set up.