Of course, for anything that is cgi/fastcgi. nginx doesn't support that.
There is also stuff running on mod_php/mod_python/mod_wcgi that is bound to apache, however these are deprecated and unstable technologies that should not be used in this decade.
There is also stuff running on mod_php/mod_python/mod_wcgi that is bound to apache, however these are deprecated and unstable technologies that should not be used in this decade.