A recruiter gave me a great piece of advice, to ask the question towards the end of the interview, "is there anything that would cause you to think I'm not quite qualified for the position," this way you can get such concerns out in front and be able to address them while it's still convenient and before they reject you for it.
I did ask those things. Don’t underestimate people’s unwillingness to look you in the eye and tell you the truth when they think you might not like it.