Kayak and OpenRasta might suit your needs.

DamonOehlman · on Dec 14, 2010

Looks like OpenRasta has a pretty solid community built around it and the general design abstraction looks pretty good.

Kayak also looks pretty nifty, but seems to be in a bit of state of flux at the moment (more so than OpenRasta).

Both added to the shortlist though :)

jacksonh · on Dec 14, 2010

I guess while I'm at it I'll throw my project into the mix. Its still very much under development though and more focused on Mono and running on OSX/Linux.

http://manosdemono.org (nothing really there right now) https://github.com/jacksonh/manos/blob/master/docs/tutorial/...