I work for a facebooked conservative. I like him a lot though. His son is one of my best friends all the way back to jr high school.
Edit: forgot to mention I consider myself a political nihilist because I find popularity contests in national office at the expense of life itself to be disgusting.
Furthermore politics seems to forget that we are all brothers and sisters that share the same fate.
Because, in general (and specific), when dealing with humans in a forum where emotions and feelings are paramount (which are most contexts) and a forum where we will need to interact with these people again (which is most places) it is far better to be nice (and taking into account the emotional state of the participants) than it is to be right (or at least to think that we're right).
This is so important it forms one of the five main human personality components, that is Agreeableness.
I'm a conservative in SV. I don't feel lonely, necessarily, but I do believe that my political views may not be favorable. And, honestly, I don't really see a point in arguing over politics with my co-workers, so it doesn't really bother me or make me lonely.
So, yes. Frequently.