It's trivial to overdose non-lethally on MDMA and there's a good possibility for permanent brain damage when it occurs, even just from a single overdose. It seems to mostly damage memory from what I've seen.
Years ago when I knew people attending EDM festivals and researched these drugs to understand the risks, it sounded like most of the harm was caused by oxidative stress resulting from the excess serotonin released by the drug vs. normally sufficient standard levels of antioxidants being overwhelmed by all the activity.
AFAIK the same is not true for LSD and shrooms, certainly not marijuana.
It's trivial to overdose non-lethally on MDMA and there's a good possibility for permanent brain damage when it occurs, even just from a single overdose. It seems to mostly damage memory from what I've seen.
Years ago when I knew people attending EDM festivals and researched these drugs to understand the risks, it sounded like most of the harm was caused by oxidative stress resulting from the excess serotonin released by the drug vs. normally sufficient standard levels of antioxidants being overwhelmed by all the activity.
AFAIK the same is not true for LSD and shrooms, certainly not marijuana.