My goal would primarily be to avoid having to make sure there's an active python installation with all the right dependencies set up on a client's computer. That's been a huge problem for me in the past during deployment (esp. older windows OS's).
A nice side benefit I foresee would be easier coordination of state between a JS front end and a Python process running specialized computations. The current best approach I'm aware of now involves sending data back and forth as JSON and trying to mirror what's going in Python with JS state management. The system described in this article where JS and Python can reference the same objects (and somewhat the same typing?) sounds like it could be an improvement.
This is also the way Java is supposed to be deployed on client machines nowadays, apparently - using the jlink tool to create a bundle of the Java runtime for your application.
