Which goes to show that the answer to "what technology should I use to start my startup in [current year]" is always "the one you know best" since Joel was a former Microsoft employee before starting Stack Overflow and his other projects.
C# is great. It's a high level programming language and it's also super-fast handling ~7.000.000 requests per second on a single server according to the following benchmark:
C# was great in 2008, then it got kind of enterprisey and closed - not it's ridiculous and getting steam into all avenues of software engineering. It's arguably the most powerful language in the world.
in the past two years .NET has become (normally/probably) the best performing GC runtime out there. With some nice features as well, and a better cross platform story.
