One of the more interesting aspects IMHO was the reason for turning off cabin lights when approaching for night landings: to acclimatise your eyes to the ambient light in case of crash. Of course the cabin crew don't disclose that...
You'd want to look at the stats another way too, though: per air mile traveled, how much more likely are you to die sitting in first class. The answer is probably "not that much", so it makes sense to enjoy the comfort.
If the difference is .0000001 % vs .0000002 %, then it doesn't really matter, does it? You're probably more likely to increase your statistical lifespan by taking a bus to the airport instead of driving, or eating a bit less fatty foods, or something else.
One thing that always annoys me a bit is when people say "life is priceless" -- because our behavior is certainly not consistent with that. We could save many human lives via a myriad of expensive policies -- for example, requiring all cars to have tank-like protective shielding. The fact that these policies are not implemented implies that we're perfectly happy to place a price on human life -- it's just a question of which particular policies save enough lives to justify the cost.
i dunno about the safest seat on the plane, but i recently found out that the most comfortable seatw on the plane--first class aside--are the exit rows seats because you get extra legroom. i used to avoid them because i thought the window seats were more uncomfortable, because they had all that exit row safety junk on them, but that's not the case.
