When a startup sells to another company, they sell their cash flow, customer/client base, products & services, IP, equipment, and employee contracts, among other things.
But is there a still a general expectation that the employees be working together in the same office, that remote organizations are too 'fragile' to risk purchasing outright?
What problems or disadvantages might companies comprised mainly of remote workforces, like 37 Signals and StackOverflow (not that either would ever sell), incur should they try to sell to another company (since most companies these days are non-remote)?