Driver support will always trail behind Linux, so it depends.
Personally, I’d be more interested into having openbsd as the standard for cloud deployments, a place currently inhabited by Ubuntu derivatives. If one could get the declarative goodness of Nix, the popularity of docker, and the reliability / security of openbsd, the world would be a better place.
No reason Nix shouldn't be able to run on OpenBSD right? Nix works on macOS quite well. It would obviously take some work to get it to configure the built in OpenBSD services but it seems like it could be worth the effort.
Personally, I’d be more interested into having openbsd as the standard for cloud deployments, a place currently inhabited by Ubuntu derivatives. If one could get the declarative goodness of Nix, the popularity of docker, and the reliability / security of openbsd, the world would be a better place.