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> still costs ~1000USD to read the ~ 1Gigabyte human genome

This piece is dropping fast though; Dante Labs will currently do it (with 30X coverage) for individuals for $500 [1]. And I believe the price for labs that do a lot of sequencing is significantly lower per-genome.

Writing is still a much bigger challenge, though. Writing something the size of the human genome is currently considered a "grand challenge" and is being tackled by HGP-Write:

https://en.wikipedia.org/wiki/Genome_Project-Write#Human_Gen...

[1] https://us.dantelabs.com/products/whole-genome-sequencing-wg...



That’s an impressive price, do you know anyone who’s done it? I’d be interested in knowing what the experience was like.

Illumina appear to be targeting 100USD right now. I think their markup on reagents is probably at least x10...

But even that’s super expensive compared to reading data from a HD... so you have to wonder where DNA as storage is viable. Unless a vastly cheaper read method becomes available.


I don't know anyone who's done it (it's still a bit too expensive for me to give it a shot) but it appears to be a fairly standard saliva sample kit that you mail in.

Yes compared to HDD it's way too expensive to read. However tape backups are also cumbersome and time-consuming to use, but the fact that you can get extremely cheap bulk storage from them means lots of big companies still use them. So I could see it maybe being competitive there (eventually).


Wow, this is the first I'm hearing of Dante Labs. That price point for 30X WGS coverage is seriously impressive.


They are just using Illumina sequencers so they are simply taking a loss on each test.




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