How well does that work on OSX? I’ve tried many times over many years, but never got a satisfactory working Python + Qt development environment working on the Mac.
With Python3 and PyQt5 it is literally as simple as "pip install pyqt5". I speak from having built and maintained multiple PyQt-based apps on MacOS.
Edit: I should say, there are MacOS-unique difficulties if you want to bundle your nice PyQt5 script into a standalone MacOS app bundle using PyInstaller. But that's a separate issue.