There is a good list here: http://peter.sh/experiments/chromium-command-line-switches/
I am currently running:
--enable-vertical-tabs
--enable-accelerated-compositing
--enable-apps
--enable-experimental-extension-apis
--enable-expose-for-tabs
--enable-fastback
--enable-gpu-plugin
--enable-gpu-rendering
--enable-preconnect
--enable-nacl
--enable-native-web-workers
--enable-webgl
--experimental-spellchecker-features
--block-nonsandboxed-plugins
--enable-accelerated-2d-canvas
--enable-aero-peek-tabs
--enable-background-mode
--enable-content-prefetch
--enable-device-motion
--enable-gview
--enable-indexed-database
--enable-login-images
--enable-new-page-info-bubble
--enable-preparsed-js-caching
--enable-video-layering
--login-manager
--nacl-broker
--prelaunch-gpu-process
--safe-plugins
--use-spdy
I'm mainly after speed (thus prefetching, leveraging GPU etc) without loosing functionality (e.g. javascript) and also cool new features like vertical tabs
