I think you need to set the scope better for the question. Easily usable by average Joe? Most secure using available for all technology / infrastructure?
signal messaging and one time pads are essentially equivalent, the former being useful only for a few bits of information, and the later is able to use the whole bandwith
e.g. selling a certain item/s at a certain price on ebay means a pre-agreed action is to occur, to be simplistic.
This does however require collusion prior.