A neighbor of mine actually had a disc explode in his drive.
I couldn't believe it at first, but sure enough, the drive sounded like a maraca when I shook it.
My Diablo II disk shattered in my mothers PC when I was in the 7th grade, we were both rather upset (me because I lost my game disc in the era they were still used for anti-piracy, her because she needed to buy a new CD drive).