The biggest difference is that 25I-NBOMe can kill you. On the other hand there isn't is single conclusive case of death by LSD poisoning.
With RCs you are essentially a guinea pig. So if you want to do LSD, do LSD, and make sure you test it first. Not only it is one of the safest drug (for the body at least) but if things take an unexpected turn (they will), decades of accumulated knowledge is a good thing.
The biggest difference is that 25I-NBOMe can kill you. On the other hand there isn't is single conclusive case of death by LSD poisoning.
With RCs you are essentially a guinea pig. So if you want to do LSD, do LSD, and make sure you test it first. Not only it is one of the safest drug (for the body at least) but if things take an unexpected turn (they will), decades of accumulated knowledge is a good thing.