A bit unrelated but I've been told biohacklabs reimplemented lab/med equipement for a hundredth (even a thousandth) of the price. Not 2015 state of art, but still usable.
Typically biohacklabs don't value their own time in the same way engineers at a company will.
Here [1] is a picture of a thermocycler, it probably took dozens of people to develop and I doubt more than 100 of the particular model are sold. On the other hand, it operates in same way as a rice cooker.
Lets do some math, it costs 1,000,000 per year to maintain the team of engineers that builds these things. They sell about 100 a year, so each one needs to sell at 10,000 just to pay for labor.
The feeling of outrage comes from the low cost cost of consumer goods. The thing is that many consumer goods (such as an electric can opener) are built at both large scales and low engineering investment - perhaps exploiting comparably cheap labor and lax patent laws in Asian. We might find that the initial engineering investment (perhaps done in the 1950s) was non-trivial, yet we aren't paying for it today.
It could be an issue of not legally being allowed to sell it cheaper, e.g. some bio/pharma company owns the patent on the tech, and chooses to sell it for $100,000, then the fact that some hackers can rip off the patent for $100 is irrelevant of the free market because they can't sell it, and any large operation would immediately face lawsuits from the patentholder if they tried to do the same thing.
For medical devices yes, but for research instruments there aren't major hurdles. You can even build instruments for medical research with virtual no certification.
Free market has blind spots.