Depends. How annoying are the ads on Google Search. Yes, I know this is HN, so annoyance levels go to 11, but most people wouldn't go searching out for a blocker if all adds were not overly obtrusive.
They're incredibly annoying. I have a 1080p screen. The entire first page of results on every search is ads. I've stopped using google.com because of this.
Or I could just use a search provider that doesn't require a "one click fix" literally every single time I use their primary service? What's your point?
Ad blockers should be a standard part of the browser, just like it is in Opera and maybe Safari. Just like the popup blocker was a standard addition in the 2000s.
I also use a DNS based filter in addition to ad blockers. Gotta love centralised ad networks - you block some hostnames and you get rid of 80% of junk automagically. The rest is the ad blocker's business.