No, because the bottleneck for most games is typically GPU performance, with a side of memory allocation. There is no magic dictating that every game needs deep instruction-level massaging, and many of the interesting bits that do need it can be turned into library code. The stack for a high performance game of 2068 might still be "low level" relative to other applications, but it has as much reason to shift towards a higher average level of abstraction as any other piece of software.
