> We have validated 63% of recoded genes by individually testing 55 segments of 50 kilobases each. We observed that 91% of tested essential genes retained functionality with limited fitness effect.
It's because I've seen your comments before and you have a consistent pattern of curtly disagreeing without adding to the conversation. It's frustrating and I want HN to be better.
Yes, they tested each piece, probably in 55 different variants of E. Coli. The gene has been converted to RNA and then to protein. That counts as "the code has been executed" in my analogy. If you're gonna be a pill at least do some further reading.
Ok I'll try. You are right I misread that - I didn't think 'tested' meant in-situ, and that plus the later statement about not trying it complete was where I was coming from.
Its just that curtness in writing is in the eye of the beholder. I strive for a concise style. That clearly isn't taken well by everybody.
