You still need to take overall ownership. Get second opinions. Do some research on use that not as the basis of making some sort of self diagnoses, but as to have a frank discourse with your doctor on your condition. Prevent the need for acute treatments by taking preventative measures that have broad scientific consensus (good diet, exercise, safety equipment, etc...). Do you have a living will and advance directives? Check to see if generic prescriptions would save you money. Proactively ask about different drug formulation if you anticipate or identify side-effects. Get justification for suggested remedies. Ensure your records are transferred or up to date when changing providers. Proactively inform your doctor of family history or environmental conditions regardless of any relevancy you expect - let them make the call but give them all the data. Research providers and providers networks, not just for expertise, which is really hard to judge, but for things like: If I call on the weekend who picks up? Your GP on her mobile? Whoever is on-call? A nurse? A referral service from the local hospital? It is wise to outsource expertise you don't have, but not management of that expertise if you can avoid it.