I can't say I've used twisted at all, but Amber had a fairly good talk at Django...

jsmeaton on Dec 2, 2015 | parent | context | favorite | on: Django 1.9 Released

I can't say I've used twisted at all, but Amber had a fairly good talk at Django Under the Hood this year on this topic: https://opbeat.com/events/duth/#twisted-and-django