I wonder how well this would work for shipping game assets in the browser. One of the nice things I miss about flash was having a single compiled object to store on the server and distribute to end users which contained all the assets and sounds needed for the game. Stuffing all your assets into a sqlite database and sending that over the wire would keep everything nice and tidy.
SQLite does mean you'll have overhead in retrieving that data, though. If you want to be able to do SQL queries on it, it's worth it, but otherwise it's probably not.
If you just want a single file, you can bundle all the assets into one and emit some metadata so you know where each file starts and ends. Emscripten's file packager does this, for example.
