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I grew up in Connecticut in the US (east coast, southern New England, adjacent to New York State). I remember Brach's displays in grocery stores, usually placed on an end cap. When I moved to Portland, Oregon (west coast) in 2006, Fred Meyer still had the Brach's candy-by-weight display. It survived until 2010 or so. I miss it. You could buy a piece of candy off the display by placing a quarter in the slot of the tiny attached lockbox. It was perhaps the last vestige of the honor system.


It has happened in plants over and over again.


Gene dose increases in plants lead to bigger vegetables and fruiting bodies. We've taken advantage of this during domestication of several species.

Gene dose increases in animals lead to total dysfunction and death in embryonic development.


There are species of fish that have gone through whole genome duplication.

https://www.nature.com/articles/s41559-023-02299-z#:~:text=P...


Dosis sola facit venenum?


dose is such a weird term for "copies"


It’s quite… historical.



Yeah, when I saw the original comment I tried to find the source of the term but wasn't able to find it.

To me it sounds like medical genetics terminology (known for terms like "penetrance", "allele", "epistasis", "locus") whereas I'm a molecular biologist/biophysicist, which has far more precise ways of describing the underlying physical model.


A term can be still used in literature for historical reasons. Both concepts are not mutually exclusive.


And in yeast there has long been evidence for WGD. See, e.g., https://pmc.ncbi.nlm.nih.gov/articles/PMC4529243/ & references therein.

Edit: I posted this without looking at the paper (which is about yeast). Doh.


In bacteria as well!


If you have access to JSTOR, the essay (with better formatting) is available here: https://www.jstor.org/stable/29781619


Right-to-left and left-to-right is how hand-knitting charts are read. But also bottom to top!


English ivy (hedera helix) can damage mortar, but grape vines don't have holdfast structures like hedera that can sink into mortar. Plus, hedera helix is so dense that rotting vegetation and sheltered animals can also cause problems. Grapevines have tendrils that grab onto and twine around something like wires or a trellis.


Commercial bananas grow from cuttings. I don’t know about the rest of the world, but in the US, plant patents protect against unauthorized propagation.


Learning about science is more rewarding to me as an amateur than hobby/indie computer programming. There are others like me, though perhaps a minority on this site. I'm sad to see this go. One of my favorite experiences as a child was visiting the Boston Science Museum.


This article lost me when it stated that Arborio rice is fluffier than basmati.


You may have misophonia. It’s not uncommon with misophonia to react with rage to eating noises. My husband cannot tolerate certain sounds, for example a dog lapping water.


I have misophonia too, related to chewing sounds. It actually developed in offices. I don’t really go to offices anymore. But the thing that definitely helped was listening to violent noises: wind storm in the forest, sound of jet engine, etc. Naturespace app for phones have some really high quality recordings. Well, that and psychotherapy. My mental health directly allows me to spend mental resources resisting all these emotions.


My son (11yo) has had this as well for the last 2.5 years. Seeing an Audiologist for treatment.

Can you elaborate a little on "listening to violent noises" approach? When do you do this, for how long? Is it graduated in intensity, like exposure therapy?

Thanks!


It is just listening to noises that would distort other unpleasant sounds in a way that they stop being distinguishable/audible. Not a therapy, just masking them temporarily. I know when the risk of disturbing noises is high, and turn on the noise beforehand, or right after it starts. Like, there is a kindergarten near my house, it is noisy, but predictable. So every day I close the window and turn on headphones during the time children are outside.

The therapy, unrelated to this coping approach, was focused on figuring out why I got sensitive to some noises in the first place during childhood. Very individual, but to give an example, appearance of stepfather in my life, whose eating habits were conflicting with the way I was raised before.


Thanks for taking the time to add these details. Will add to the arsenal of tools. Best of luck!


I got it to work with Safari on iOS 15.7.2, iPhone 7+. Firefox was a no go, I tried it first.


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