With MicroPython you can have C drivers and just do the MicroPython bindings. I do not see the benefits of having yet another interpreted IoT language and it does not make sense to do the drivers in the interpreted language itself.
The consequences of a type unsoundness in TypeScript are typically much more benign (an exception typically) than in C (a buffer overflow, arbitrary code execution, etc.). Also the application logic is more visible in TypeScript just due to it being higher-level - there isn't so much low-level detail (ever done JSON in C?) so less chance for a mistake.